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TECHNOLOGY BASED INNOVATIVE COURSES

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DR. LEE'S RESOUCES FOR STRUCTURAL STUDIES

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a) Synchrotron X-ray Source (National Synchrotron Light Source II at Brookhaven National Laboratory), b) In-house X-ray Source, c) High-throughput Crystallization Screening System (Crystal Gryphon, Art Robbins Instruments), d) Automatic Protein Crystal Imaging System (CrysCam Digital Microscope, Art Robbins Instruments) 

FEATURED CRYSTAL STRUCTURES

PfPMT + SAH + pEA

PDB code: 5UJB

Structure and reaction mechanism of phosphoethanolamine methyltransferase from the malaria parasite

Plasmodium falciparum - an anti-parastic drug target.  J Biol Chem 287, 1426-34 

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AtIPMDH2 + IPM

PDB code: 5J32

Structure and mechanism of isopropylmalate dehydrogenase from Arabdiopsis thaliana: insights on leucine and aliphatic glucosinolate biosynthesis 

J Biol Chem 291, 13421-30 

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AtIPMDH2 + NAD

PDB code: 5J33 

Structure and mechanism of isopropylmalate dehydrogenase from Arabdiopsis thaliana: insights on leucine and aliphatic glucosinolate biosynthesis

J Biol Chem 291, 13421-30 

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NolR + DNA

PDB code: 4OMY

Structural basis for regulation of rhizobial nodulation and symbiosis gene expression by the regulatory protein NolR

Proc Natl Acad Sci USA 111, 6509-14

DR. LEE'S STRUCTURES IN PDB

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